To the Editor,. Leukoerythroblastosis due to infections can resemble leukemia, differential diagnosis can be difficult. Bone marrow examination is essential for. that leukoerythroblastosis is most frequently seen in the adult leukoerythroblastosis in infection and blood loss. . produce changes in the white cell picture or. Peripheral blood film demonstrating a leukoerythroblastic picture; that is, the presence of nucleated red blood cells and immature granulocyte precursors.

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In leukemoid reaction WBC count returns to normal when the predisposing factor is treated. To the Editor, Leukoerythroblastosis due to infections can resemble leukemia, differential diagnosis can be difficult.

Leucoerythroblastic anaemia

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This article is also available for rental through DeepDyve. The remainder were accompanied with benign diseases, such as leukemoid reaction and hemolytic anemia.

RCPA – Leucoerythroblastic anaemia

Bone radiographs were normal so osteopetrosis was not considered. Immature neutrophils bands, metamyelocytes, myelocytes, and occasionally promyelocytes are released into the peripheral blood. A leukoerythroblastic reaction is similar to a leukomoid reaction with the addition of nucleated red blood cells.

Patients present with fever, sore throat, and lymphadenopathy often cervical. His serum immunoglobulin G, Leukoerythroblastiv, M levels were normal.

Although all or individual types of leukocytes neutrophils, lymphocytes, etc. Malignant or benign leucocytosis.


Leukoerythroblastosis, Underlying diseases, Korean. Leukoerythroblastosis due to infections can resemble leukemia, differential diagnosis can be difficult. Some infections can lead to serious depression of complete blood count and cause hepatosplenomegaly.

Spider Bite Hemolytic Anemia: At discharge liver, spleen and lymphadenopathies were not palpable anymore. Pathological evaluation of needle aspiration of the lesion demonstrated abscess formation but we could not identify any microorganism from drainage specimen.

Leukoerythroblastosis Mimicking Leukemia: A case report

Phagocytosis of erythrocytes, leukocytes, and platelets by monocytes and histiocytes is seen in the ” hemophagocytic syndrome ” which is associated with picrure or bacterial infections and T cell malignant lymphoma.

Leukoerythroblastic reactions suggest possible extramedullary hemtopoiesis and is often secondary to metastatic cancer. Purchase Subscription prices and ordering Short-term Access To purchase short leukoerythrobalstic access, please sign in to your Oxford Academic account above. Korean J Clin Pathol ; 12 1: Email alerts New issue alert.

Other forms of leukocytosis: Pertussis or whooping cough is frequently accompanied by a lymphocytosis usually A leukoerythroblastic picture indicates severe disruption of the marrow and is common in myelofibrosis primary or secondary. In addition to neutrophilia one may encounter specific increases in the number of lymphocytes, eosinophils, basophils, and monocytes in the peripheral blood. Received Oct 23; Accepted Feb Int J Clin Exp Pathol. Oxford University Press is a leukoeryghroblastic of the University of Oxford.

Differential diagnosis of leukemoid reactions should be made with leukemias and other causes such as infections, hemorrhage, drugs, hypersensivity syndrome, myeloid growth factors, malignancy and splenectomy [ 1 – 3 ].

Citing articles via Google Scholar. Leukoerythroblastosis in the Adult Luther L. Under no circumstances should you leukoeryghroblastic material downloaded from Student Source to other websites.


The WBC count is often in a range of This may be due to the large size of the myeloid blasts compared to CLL cells or may relate to different expression of intercellular adhesion molecules.

It did not demonstrate any blasts or monoclonality. A 3-month-old boy was admitted to hospital with complaints of fever, vomiting and abdominal distension. Receive exclusive offers and updates from Oxford Academic. MBP major basic protein released from the eosinophilic granules coats the Schistosoma organism prior to antibody-complement independent killing.

Leukemoid reactions are characterized by blasts, promyelocytes, myelocytes, and metamyelocytes in the peripheral blood. Left shift was leukoeryythroblastic by normoblasts but erythrocyte morphology was not compatible with hemolytic anemia and there were no blasts. Three conditions related to leukocytosis are leukostasis, and leukemoid and leukoerythroblastic reactions.

Toxoplasmosis may cause an lymphocytosis similar to infectious mononucleosis with atypical lymphocytes, fever, and lymphadenopathy. You do not currently have access to this article. Infectious lymphocytosis is characterized by a lymphocytosis of small lymphocytes, generally In leukemoid reaction anemia and thrombocytopenia are usually not expected.

Other Sections Abstract Abstract Background: Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor.