Cemento-ossifying fibroma is classified as an osteogenic tumor, defined as a well -differentiated tumor, occasionally encapsulated, comprising fibrous tissue. Abstract. Introduction: Cemento-ossifying fibroma is a benign fibro-osseous maxillary tumor belonging to the same category as fibrous dysplasia and. Background: Cemento-Ossifying Fibroma (COF) is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other.

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Cemento-ossifying fibroma | Radiology Reference Article |

The variable calcifications represent various stages of deposition of bone and cementum. Treatment consists of surgical excision, including the periosteum and scaling of adjacent teeth. Clinical, radiographic and histopathologic features of COF and other fibro-osseous lesions are overlapping and may cause confusion in classification, diagnosis and treatment.

Histopathological picture had shown highly cellular fields with some calcified areas. Extraoral and intraoral photographs showing ceemento large diffused swelling with buccal vestibular obliteration over left side Click here to view. Edit article Share article View revision history. Cellular component was composed of fibroblasts arranged in different patterns. It was slightly pedunculated with what appeared to be a broad-based attachment.

Occlusal radiograph showed well-defined expansion of both the buccal and lingual cortical plates arising from lower right first molar region, with evidence of ill-defined diffuse septa, suggesting a multi-locular appearance with diffuse irregular radiopacity within the largely radiolucent lesion Figure 3.

Case 1 Case 1. With female predilection over men 5: Malkunje Open Journal of Stomatology. It was bony hard in consistency, and tender along the mental nerve region. Discussion InMenzel first described a variant of ossifying fibroma in the mandible, and called it as COF.


Case Reports in Dentistry

Open in a separate window. Case Report A 35 year old female patient reported with a complaint of swelling ossifiyng the lower left jaw since past 2 months [ Figure 1 ]. Cemento – ossifying fibroma is a benign fibro-osseous- tumor. June 25, ; Published date: Although peripheral ossifying fibroma is benign, reactive lesion, the recurrence rate is fairly high.

Cemento-Ossifying Fibroma- A Case Report | OMICS International

Select your language of interest to view the total content in your interested language. The recent WHO edition of the classification of odontogenic neoplasms ossigying replaced the term Cemento-ossifying fibroma with Ossifying Fibroma [ 8 ].

This may be explained by the fact that the lesion might develop from an ectopic periodontal membrane, and thus occur outside the jaws. Because the clinical appearance of fiborma various lesions can be remarkably similar, classification is based on their distinct histologic differences.

Even then, the differences between the broad spectrum of ossifying fibromas remains unclear. Eversole and Rovin [ 17 ] stated the similar sex and site predilection of pyogenic granuloma. The lesion was well demarcated and pedunculated measuring approximately Figure 3.

Int J Oral Maxillofac Surg. However, in most cases both features are present, warranting the generic term cemento-ossifying fibromas 1. Also, despite the stage of cemeto, the lesion of COF is always well circumscribed ossifyng demarcated from surrounding bone, in contrast to true fibrous dysplasia.

A more aggressive form of COF which occurs in younger individuals has been designated as Juvenile cemento-ossifying fibroma [ 10 ]. Abstract Cemento-ossifying fibromas are rare fibro-osseous benign neoplasms that affect the jaws.

Cemento-ossifying fibromas COFs are benign lesions affecting the jaws and other craniofacial bones. Peripheral ossifying fibroma is thought to be either reactive or neoplastic in nature.


The diagnosis of cemento-ossifying fibroma of the jaw can be established based on clinical, radiographic and histo-pathological features. The following case report attempts to differentiate fihroma lesions presenting with odsifying clinical, radiographic and histologic presentations; as well as describe the varying manifestations of COF, with reference to previous literature.

Address correspondence and reprint request to: Some entities worth considering include Cakir B, Karaday N. Lateral occlusal view shows dense expansion of buccal cortical plate. In conclusion, COF should be considered in the differential diagnosis of lesions that present clinically as a slow-growing tumor, especially in females.

A slowly growing pink soft-tissue nodule in the anterior maxilla of an adolescent should raise suspicion of a POF. High power histopathological picture showing lamellar bone with osteoblastic rimming and psammomatous-like nodules and calcifications in the fibrous stroma haematoxylin-eosin x Complete surgical removal of the lesion was done Figures 7 and 8 and patient was reviewed after 4 months Figure 9.

An incisional biopsy was performed, histological examination revealed as tightly cellular connective tissue stroma with abundant spindle shaped hyperchromatic fibroblasts and sparely collagen fibres along with scattered numerous irregular shaped basophilic cementum like tissue.

Cemento-ossifying fibroma of the petromastoid region: Most of the lesions typically show slow and often expansile growth, centrally within the jaw and characteristically behave in a benign form, but occasionally they may present as an aggressive gigantiform lesion. There is a female ossifyjng in these lesions, with a ratio ranging from 2: