Download Citation on ResearchGate | Carcinoma mucinoso de mama: Un análisis de casos apareados | Mucinous carcinoma (MC) of the breast is an. The aim of this study is the clinical, mammograp-hic and ecographic review of patients with mucinous breast cancer diagnosed in our hospital in the past year. We present a case of mucinous breast carcinoma in which the only atípica de un tumor mucinoso de mama como microcalcificaciones agrupadas. Radiología .

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Microscopically, it is formed by large mucin lakes surrounded by mucus-producing cancer cells. There are two histological presentations with different imaging features and prognoses: Typically, carcunoma are associated with disseminated metastasic disease and imply a poor prognosis.

Simple mastectomy is sometimes required when the tumor is bulky, deep-seated or painful. Breast neoplasm; Mucinous carcinoma; Mammography; Ultrasonography; Magnetic resonance imaging.

The retroperitoneal mass was treated with radiotherapy. Edit article Share article View revision history.

Frozen biopsy revealed metastasis to the breast from a mucosecretor adenocarcinoma with “signet ring cells” possibly of colonic origin. Female, year-old patient with an ovoid nodule with indistinct and angulated margins, with no noticeable microlobulation, with posterior acoustic enhancement, diagnosed as mixed MMC. Imaging findings and accuracy of core needle biopsy in mucinous carcinoma of the breast. J Surg Oncol ; MRI features of pure and mixed forms with histopathologic correlation.

Color mapping of wash-in B and kinetic czrcinoma C showing slight maka at the early phase with progressive enhancement pattern. New author database being installed, click here for details.

Pure type shows indolent growth, while the mixed type presents variable biological behavior, sometimes similar to NS-IDCs The histopathological differential diagnosis is based on the presence of an in situ component in the proximity of the main tumor in primary breast cancers, but this is inconsistent.


The mucinosi findings may suggest both subtypes of MMCs, pure and mixed ones.

Mucinous carcinoma of the breast: a case report and review of the literature.

In addittion, the presence of intermediate signal on T2-weighted images suggests the mixed type of MMC. On postcontrast images, benign-appearing kinetics with gradual and persistent enhancement is typical and so they can be easily mistaken for a benign lesion. As times the lesion can be isoechoic to breast tissue on ultrasound which can make diagnosis difficult 3. The mixed type presents a greater amount of neoplastic cells not involved by mucin, generally in association czrcinoma a smaller amount of extracellular mucin, which implies intermediate characteristics between the pure type and nonspecific invasive ductal carcinoma NS-IDCfor this reason sometimes referred to as “IDC with mucinous differentiation” 6,7.

Its clinical incidence varies from 0. Within metastatic disease to the breast, colon cancer metastases are rare.

IDC Type: Mucinous Carcinoma of the Breast

At mammography, the pure type correlates with circumscribed or micro-lobulated margins, which present a direct relationship with the amount of extracellular mucin 16as carcinomma on Figure 1. Imaging findings in mucin-containing carcinomas of the breast: Metastases to the breast are very rare.

The patient was treated with chemotherapy, 5-fluorouracil and irinotecam stopped for intoleranceand capecitabine and Utefos. Since then, fewer than 10 cases have been mamma in the literature 1, Pure and mixed mucinous carcinoma of the breast: Diagnosis and natural history of extramammary tumors metastatic to the breast.

In most series, more than 80 percent of patients succumb within one year.

Mucinous carcinoma of the breast | Radiology Reference Article |

Typically, colorectal carcinomas are positive for CK20, whereas this is exceptional in primary breast carcinoma 10, The first cases of breast metastasis from an adenocarcinoma of the colon and rectum were reported by McIntosh in 4.


Some studies have found that the average age at diagnosis is in the 60s or early 70s. Rev Esp Enferm Dig ; Overall the tendency to metastasize is less than for other types of cancer e. A definitive histopathologic report confirmed metastases to the breast from a mucinous adenocarcinoma of intestinal origin, based on the presence of ductal in situ carcinoma, a colonic type pattern with “signet ring cells”, and an immunohistochemical study that was negative for estrogen and progesterone receptors, and GCDFP, and positive for CEA cell expression and cytokeratin 20 CK 20 Fig.

Mixed mucinous tumors may exhibit lower ADC values, similarly to other breast cancer subtypes. Histological diagnosis The diagnosis of mucinous neoplasm may be suspected at fine-needle aspiration biopsy FNABalthough with low accuracy in the differentiation between benign mucoceles and malignant mucinous lesions MMC. Dynamic contrast-enhanced, T1-weighted images with fat suppression and subtraction, at the second and fifth minutes, demonstrating predominantly ring-shaped and progressive enhancement, and also marked enhancement of the septa within the lesion.

Cancers metastatic to the breast. Differences exist between cells of pure and mixed forms Ultrastruct Pathol ; Accepted after revision March 7, High ADC values may be associated with the presence of extracellular mucin and low tumor cellularity. The case presented mucinpso this report had an unusual mammographic appearance, due to the presence of microcalcifications.

Sometimes mucinous breast carcinomas show a ductal infiltrating solid component, mucinosso presence of “signet ring cells” being uncommon. Sonographic appearance of mucinous carcinoma of the breast.

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