Int J Vitam Nutr Res. ;65(1) Hyper-beta-carotenemia unrelated to diet: a case of brain tumor. Olmedilla B(1), Granado F, Blanco I. Author information. Carotenemia is a harmless condition in which the skin turns a yellowish color from eating lots of certain foods. Unlike jaundice, the whites of the eyes remain. Carotenemia is the presence of high levels of beta carotene in the blood. Carotenemia is also sometimes called carotenodermia.

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Sclera and mucous membranes are spared. The primary factor differentiating carotenoderma from jaundice is the characteristic sparing of the sclerae in carotenoderma, which would be involved in jaundice if the bilirubin is at a level to carotensmia skin findings. Dermatopathia pigmentosa reticularis Pigmentatio reticularis faciei et colli Reticulate acropigmentation of Kitamura Reticular pigmented anomaly of the flexures Naegeli—Franceschetti—Jadassohn syndrome Dyskeratosis congenita X-linked reticulate pigmentary disorder Galli—Galli disease Revesz syndrome.

A single carottenemia of squash provides more than 7, international units of vitamin A, or percent of a person’s recommended daily serving. After a return to a more normal diet, the carotenemia color will disappear in 3 or 4 weeks.


This is called primary carotenaemia and appears several weeks after increased ingestion of the responsible foods. This article does not provide medical advice. Although Alzheimer’s disease has been associated with carotenoderma in some reports, most studies on serum carotenoids in these patients show that their levels of carotenoids and retinol are depressed, and may be associated with the development of dementia.


Carotenoids are deposited in the intercellular lipids of the stratum corneumand the color change is most prominent in regions of increased sweating and thickness of this layer. Differential Diagnosis Jaundice Hyperbilirubinemia. Types, Causes, Signs, Symptoms, Treatment.

The physician will also examine the sclera to see whether it is yellow in color as that may be a case of jaundice.

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Is the incidence of registrable age-related macular degeneration increasing? These include hepatitisurticaria, aplastic anemia, and a retinopathy characterized by yellow deposits and subsequent visual field defects.

It tends to be more common in the restricting subtype of this disease, and is associated with numerous other dermatologic manifestations, such as brittle hair and nails, lanugo -like body hair, and xerosis. Other studies have shown positive effects with high levels of dietary beta-carotene as well as use of supplemental lycopene and lutein. Your child’s skin turns a yellow-orange color because of the pigment carotene found in yellow vegetables squash, carrots, sweet potatoesas well as some fruits such as oranges, apricots, and peaches.

Patients should be advised what foods contain carotene and advised not to overeat these foods. Carotenemia is a condition which does not need any specific aggressive treatment and can be managed with diet alone. Infants with this condition should not be taken off prescribed vitamin supplements unless advised to do so by the child’s pediatrician. It is of note that lycopenemia is specifically associated with discoloration of the soft palate and deposition in the liver parenchyma.


Krajcovicova-Kudlackova M, Dusinska M. Disease states associated with carotenoderma include hypothyroidismdiabetes czrotenemiaanorexia nervosanephrotic syndrome, and liver disease. This happens most often between 6 and 18 months of age.

Carotenemia | Pediatrics Clerkship | The University of Chicago

Carotene is also found in green vegetables for example green beans and peas. Retrieved from ” https: In addition to that source of carotene, infants are usually prescribed a liquid vitamin supplement, such as Carotenemix, which contains vitamin A.

A issue of “Pediatric Dermatology” explains that some parents may think their infants have jaundice, but carotenemia is a different condition and may be common in young children. This condition is called argyria. With the increasing use of supplements to treat patients with AMD and other conditions, physicians should carofenemia their awareness of this entity.

Argyria Chrysiasis Arsenic poisoning Lead poisoning Titanium metallic discoloration. There are three main mechanisms involved in hypercarotenemia: Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters. Top 10 Painkillers in the US.


In most instances it caroteemia associated with large consumption of carotene in the diet. Vitamin A levels should remain normal but are sometimes slightly high. Hypervitaminosis A may cause alopecia, bone pain, skin desquamation, anorexia, or hepatomegaly, 3 but carotenemia is thought to be a benign disorder, causing only skin discoloration.